Nicolas Gonzalez, Angel Di Maria and Lionel Messi all scored for Argentina.
Gonzalez scored in the 35th minute to give Argentina an early lead.
Argentina lead 1-0 in the first half and scored two more goals in the second half.
De Maria doubled the lead in the 79th minute.
Then in the 82nd minute of the game, captain Messi scored a goal to give Argentina a comfortable 3-0 victory.
With this victory, Argentina has added 38 points in 16 games.
Argentina, who have already been selected in the World Cup, are in second place in the table. Venezuela is at the bottom with 10 points.
From the South American selection, four nations will directly qualify for the World Cup. Brazil, Argentina, Ecuador and Uruguay have already qualified for the World Cup in Qatar. The fifth-place team will play in the playoffs. Among them are Peru, Colombia and Chile.